In this report on the evaluation of ‘Keep Well’ Waves 1-4 in NHS Greater Glasgow & Clyde, I have endeavoured to do three things; firstly, to provide an analysis of the original policy context and intended purpose of ‘Keep Well’; secondly, to set out clearly the evaluation findings from Keep Well’s many distinctive constituent components as the programme evolved towards a mainstreamed model; and, thirdly, to identify wider transferable lessons for delivery of preventive anticipatory care in NHS GG&C. This report covers the first five years (2006-2010) of the Keep Well programme in NHS GG&C. Over this period, Keep Well has progressively extended its coverage of our Health Board’s most deprived communities, always maintaining a commitment to supporting general practice in their central role at the heart of anticipatory care. By 2010, the Keep Well programme was operational across 52 primary prevention practices (map), which has now expanded to 100 Practices.